It is extremely important that the patients give their doctor information about any allergies and/or usage of any other medicines including over-the-counter or prescription drugs, vitamins, supplements or herbal medicine before starting the chemotherapy. This is because an exposure to certain compounds or allergens can increase the risk of developing an allergic reaction to the chemotherapy. The doctor can then decide the right medication. Skin tests to certain chemotherapy drugs have also been developed to assess the risk of allergy(3), which must be performed at the required stage of drug administration(4). For certain drugs like Paclitaxel, antihistamines and corticosteroids can be given prior to the chemotherapy(4). Administering the drugs slowly over 30-60 minutes can help for some drugs ., Teniposide and Etoposide(3).
Apoquel® was approved by the FDA and launched by Zoetis in January 2014 for the treatment of itch, most often caused by allergic dermatitis. Unfortunately, the demand quickly exceeded the manufacturing capacity and this led to limited availability and backorders. Remember this if you have asked your veterinarian about Apoquel® but were unable to try this medication for you're your own dog. In many cases, only veterinary dermatologists have increased access to this medication. Zoetis anticipates increased availability of the drug in the summer of 2015. The drug has a rapid onset of action with decreased itching often noted within a few days. This medication is typically given twice daily for 2 weeks, and then tapered to once daily. Because the drug has a short half-life, tapering to lower doses is typically not possible.