Prednisolone steroid tablets for asthma

Prednisone is a drug that belongs to the corticosteroid drug class, and is an anti-inflammatory and immune system suppressant. It's used to treat a variety of diseases and conditions, for example: inflammatory bowel disease (Crohn's disease and ulcerative colitis ), lupus , asthma , cancers , and several types of arthritis .

Common side effects are weight gain , headache , fluid retention, and muscle weakness . Other effects and adverse events include glaucoma , cataracts , obesity , facial hair growth, moon face, and growth retardation in children. This medicine also causes psychiatric problems, for example: depression , insomnia , mood swings , personality changes, and psychotic behavior. Serious side effects include reactions to diabetes drugs , infections, and necrosis of the hips and joints.

Corticosteroids like prednisone, have many drug interactions ; examples include: estrogens , phenytoin ( Dilantin ), diuretics, warfarin ( Coumadin , Jantoven ), and diabetes drugs . Prednisone is available as tablets of 1, , 10, 20, and 50 mg; extended release tablets of 1, 2, and 5mg; and oral solution of 5mg/5ml. It's use during the first trimester of pregnancy may cause cleft palate . This medicine is secreted in breast milk and can cause side effects in infants who are nursing . You should not stop taking prednisone abruptly because it can cause withdrawal symptoms and adrenal failure. Talk with your doctor, pharmacist, or other medical professional if you have questions about beta-blockers. Talk with your doctor, pharmacist, or other medical professional if you have questions about prednisone.

If you notice other effects not listed above, contact your doctor or pharmacist. In the US -Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Along with its useful effects, prednisolone can cause unwanted side-effects which your doctor will discuss with you. The benefits of taking prednisolone usually outweigh the side-effects, although unwanted effects can sometimes be troublesome. The table below contains some of the most common ones. You will find a full list in the manufacturer's information leaflet supplied with your medicine. Although not everyone experiences side-effects, and some will improve as your body adjusts to the new medicine, you should speak with your doctor or pharmacist if you become concerned about any of the following:

The initial dosage of prednisolone sodium phosphate oral solution may vary from 5 mL to 60 mL (5 to 60 mg prednisolone base) per day depending on the disease being treated. Prednisolone sodium may interact with barbiturates, phenytoin, ephedrine, rifampin, cyclosporine, estrogens , ketoconazole, warfarin, aspirin or other non-steroidal anti-inflammatory drugs ( NSAIDs ), diuretics , amphotericin-B, digitalis, anticholinesterase drugs, certain vaccines , and anti-diabetic medications. Tell your doctor all medications and supplements you use and all vaccines you recently received. During pregnancy, prednisolone sodium should be used only if prescribed. Prednisolone sodium passes into breast milk and may harm a nursing baby. Consult your doctor before breastfeeding.

Dosing should be individualized based on disease and patient response:

Initial dose: 5 to 60 mg orally per day; may be give once a day or in divided doses
Maintenance dose: Adjust or maintain initial dose until a satisfactory response is obtained; then, gradually in small decrements at appropriate intervals decrease to the lowest dose that maintains an adequate clinical response

Comments:
-Exogenous corticosteroids suppress adrenocorticoid activity the least when given at the time of maximal activity; consider time of maximal adrenal cortex activity (2 AM to 8 AM) when dosing.
-Alternate day therapy may be considered in patients requiring long-term treatment; it may be necessary to return to a full suppressive daily dose in the event of acute flare-ups.

Uses: As an anti-inflammatory or immunosuppressive agent when corticosteroid therapy is appropriate, such as treatment of certain allergic states; nervous system, neoplastic, or renal conditions; endocrine, rheumatologic, or hematologic disorders; collagen, dermatologic, ophthalmic, respiratory, or gastrointestinal diseases; specific infectious diseases or conditions related to organ transplantation.

Prednisolone steroid tablets for asthma

prednisolone steroid tablets for asthma

Dosing should be individualized based on disease and patient response:

Initial dose: 5 to 60 mg orally per day; may be give once a day or in divided doses
Maintenance dose: Adjust or maintain initial dose until a satisfactory response is obtained; then, gradually in small decrements at appropriate intervals decrease to the lowest dose that maintains an adequate clinical response

Comments:
-Exogenous corticosteroids suppress adrenocorticoid activity the least when given at the time of maximal activity; consider time of maximal adrenal cortex activity (2 AM to 8 AM) when dosing.
-Alternate day therapy may be considered in patients requiring long-term treatment; it may be necessary to return to a full suppressive daily dose in the event of acute flare-ups.

Uses: As an anti-inflammatory or immunosuppressive agent when corticosteroid therapy is appropriate, such as treatment of certain allergic states; nervous system, neoplastic, or renal conditions; endocrine, rheumatologic, or hematologic disorders; collagen, dermatologic, ophthalmic, respiratory, or gastrointestinal diseases; specific infectious diseases or conditions related to organ transplantation.

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